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Question 1 1. Antibodies directed against HIV can enhance the infection by facilitating entry of virus into immune cells. Answer True False 2 points Question 2 1. The most common mode of transmission of HIV worldwide is which of the following (select one)? Answer A Sharing of intravenous . B. Heterosexual contact needles C. Blood D . Transfusion Homosexual contact 2 points Question 3 1. Match the role in HIV infection in the concept map below of the following HIV proteins Answer Answer 1 Integrase . 2 Rev . 3 Nef . 4 GP120 . 5 Tat . 6 Vpu . 7 Vpr . 8 Reverse Transcriptase . 9 Vif . 5 points Question 4 1. Match the following phases of a HIV infection with their associated symptoms or clinical parameters. Answer Helper T-cell levels below 200/ml Read Answer Items for Question 4 Steady Decline in Helper T-cell Answer A Symptomatic . B. Acute Phase Phase/AIDS C. Asymptomatic Phase levels Read Answer Items for Question 4 Elevated levels of Cytoxic T-cells Read Answer Items for Question 4 Flu-Like Symptoms Read Answer Items for Question 4 Initial infection of memory T-cells Read Answer Items for Question 4 Highest level of viremia Read Answer Items for Question 4 3 points Question 5 1. It is estimated that the genetic diversity of HIV in a single individual exceeds that of the worldwide diversity of Influenza A during a typical pandemic. Answer True False 2 points Question 6 1. Individuals infected with HIV are much more likley to develop agressive cancers such as Kaposi's sarcoma and B-cell lymphoma. Explain why this is the case (4-5 sentences max). Answer Press Tab to enter the content editor. For the toolbar, press ALT+F10 (PC) or ALT+FN+F10 (Mac). Path: p Words:0 2 points Question 7 1. Visit the World Health Organization (WHO) website on HIV/AIDs (www.who.int/hiv/en/) and study the statistics on world wide infections. Fill in the blanks below for the statistic for HIV infection as of the end of 2011. Blank 1 million individuals worldwide have died of AIDs since its discovery in the early 1980s. Blank 2 million individuals die in 2011 from AIDs Blank 3 million individuals worldwide are infected by HIV. Blank 4 million individuals were newly infected with HIV in 2011. Answer 2 points Question 8 1. One of the features of HIV that has made it such a severe global health issue is the fact that it possess an asymptomatic phase that can last many years. Explain in 5-6 sentences why HIV has a long asymptomatic phase and how this has contributed to the severity and spread of the AIDs pandemic. Answer Press Tab to enter the content editor. For the toolbar, press ALT+F10 (PC) or ALT+FN+F10 (Mac). Path: p Words:0 2 points