Question 1
1.
Antibodies directed against HIV can enhance the infection by facilitating entry of virus into
immune cells.
Answer
True
False
2 points

Question 2
1.
The most common mode of transmission of HIV worldwide is which of the following (select
one)?
Answer
A Sharing of intravenous
.
B. Heterosexual contact

needles

C. Blood
D
.

Transfusion
Homosexual contact
2 points

Question 3
1.
Match the role in HIV infection in the concept map below of the following HIV proteins

Answer
Answer
1 Integrase
.
2 Rev
.
3 Nef
.
4 GP120
.
5 Tat
.
6 Vpu
.
7 Vpr
.
8 Reverse Transcriptase
.
9 Vif
.

5 points

Question 4
1.
Match the following phases of a HIV infection with their associated symptoms or clinical
parameters.
Answer

Helper T-cell
levels below
200/ml
Read Answer Items for
Question 4

Steady Decline in
Helper T-cell

Answer
A Symptomatic
.
B. Acute Phase

Phase/AIDS

C. Asymptomatic

Phase

levels
Read Answer Items for
Question 4

Elevated levels of
Cytoxic T-cells
Read Answer Items for
Question 4

Flu-Like
Symptoms
Read Answer Items for
Question 4

Initial infection of
memory T-cells
Read Answer Items for
Question 4

Highest level of
viremia
Read Answer Items for
Question 4
3 points

Question 5
1.
It is estimated that the genetic diversity of HIV in a single individual exceeds that of the
worldwide diversity of Influenza A during a typical pandemic.
Answer
True
False
2 points

Question 6
1.
Individuals infected with HIV are much more likley to develop agressive cancers such as
Kaposi's sarcoma and B-cell lymphoma. Explain why this is the case (4-5 sentences max).
Answer

Press Tab to enter the content editor. For the toolbar, press ALT+F10 (PC) or ALT+FN+F10 (Mac).

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2 points

Question 7
1.
Visit the World Health Organization (WHO) website on HIV/AIDs (www.who.int/hiv/en/) and study the statistics on
world wide infections. Fill in the blanks below for the statistic for HIV infection as of the end of 2011.
Blank 1 million individuals worldwide have died of AIDs since its discovery in the early 1980s.
Blank 2 million individuals die in 2011 from AIDs
Blank 3 million individuals worldwide are infected by HIV.
Blank 4 million individuals were newly infected with HIV in 2011.
Answer
2 points

Question 8
1.
One of the features of HIV that has made it such a severe global health issue is the fact that it
possess an asymptomatic phase that can last many years. Explain in 5-6 sentences why HIV has
a long asymptomatic phase and how this has contributed to the severity and spread of the AIDs
pandemic.
Answer

Press Tab to enter the content editor. For the toolbar, press ALT+F10 (PC) or ALT+FN+F10 (Mac).

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Words:0
2 points