About Sickle Cell Disease and Biocultural…

About Sickle Cell Disease and Biocultural…

About Sickle Cell Disease and Biocultural Evolution,see question on the file.

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Question 1:Why is sickle cell anemia more common in certain regions of the world?
What is the link between the sickle-cell, malaria and human alteration of the
environment?

Question 2:Looking to the future, what factors (environmental, genetic, or social)
could cause alteration in frequencies of the sickle cell in human populations? What
changes to the sickle-cell allele do you envision as most likely, and why?

Instructions

Explore sickle cell disease and its evolutionary basis in greater depth by reading information from
the web sites below. Also, make sure to consult pages 317-320 of your textbook for a discussion
of the topic.
Symptoms and Genetics of Sickle Cell Disease
http://ghr.nlm.nih.gov/condition/sickle-cell-disease
A Mutation Story (PBS Evolution Library)
http://www.pbs.org/wgbh/evolution/library/01/2/l_012_02.html
New York Times article on the evolution of the sickle cell allele
http://www.nytimes.com/2001/06/22/us/gene-study-dates-malaria-to-the-advent-of-farming.html?
scp=5&sq=sickle%20cell%20anemia%20malaria&st=cse